Richtlijnen en studies (nationaal en internationaal)
Het gebruik van siliconen littekenverband & gel is wereldwijd door zorgprofessionals zeer veelvuldig bestudeerd en vele studies laten een positief effect zien op de behandeling van afwijkende littekens.
Studies waaraan wordt gerefereerd in onze brochures
1. Evidence-Based Scar Management: How to Improve Results with Technique and Technology | I. Khansa |2016Sep;138(3 Suppl):165S-78S
2. International Clinical Recommendations on Scar Management | Thomas A. Mustoe | 2002 Aug;110(2):560-71
3. Evolution of silicone therapy and mechanism of action in scar management | Thomas A. Mustoe | 2008 Jan;32(1):82-92
4. Scar Management Practical Guidelines - Esther Middelkoop | 2014 Aug;67(8):1017-25
5. Management of scars: updated practical guidelines and use of silicones | S. Meaume | 2014 Jul-Aug;24(4):435-43
6. Scar revision in children: Clinical situations and solutions | V. Duquennoy-Martinot | 2016 Oct;61(5):578-588
7. Silicones in the rehabilitation of burns | Eric van den Kerckhove | Burns | 2001 May;27(3):205-14
8. A Randomized Clinical Trial to Study the Effect of Silicone Gel Dressing and Pressure Therapy on PosttraumaticHypertrophic Scars | Cecilla Wai Ping Li-Tjang | Burns | 2010 May-Jun;31(3):448-57
9. Practice guidelines for the application of nonsilicone or silicone gels and gel sheets after burn injury | B. Nedelec | 2015 May-Jun;36(3):345-74
Aanvullende studies
1.Bayat A, McGrouther DA, Ferguson MW. Skin scarring.BMJ.2003;326:88–92. doi: 10.1136/bmj.326.7380.88.[PMC free article][PubMed][Cross Ref]
2.Bock O, Schmid-Ott G, Malewski P, Mrowietz U. Quality of life of patients with keloid and hypertrophic scarring.Arch Dermatol Res.2006;297:433–438. doi: 10.1007/s00403-006-0651-7.[PubMed][Cross Ref]
3.Berman B, Perez OA, Konda S, et al. A review of the biologic effects, clinical efficacy, and safety of silicone elastomer sheeting for hypertrophic and keloid scar treatment and management.Dermatol Surg.2007;33:1291–1303. doi: 10.1111/j.1524-4725.2007.33280.x.[PubMed][Cross Ref]
4.Puri N, Talwar A. The efficacy of silicone gel for the treatment of hypertrophic scars and keloids.J Cutan Aesthet Surg.2009;2:104–106. doi: 10.4103/0974-2077.58527.[PMC free article][PubMed][Cross Ref]
5.Signorini M, Clementoni MT. Clinical evaluation of a new self-drying silicone gel in the treatment of scars: a preliminary report.Aesthetic Plast Surg.2007;31:183–187. doi: 10.1007/s00266-005-0122-0.[PubMed][Cross Ref]
6.Chittoria RK, Padi TR. A prospective, randomized, placebo controlled, double blind study of silicone gel in prevention of hypertrophic scar at donar site of skin grafting.J Cutan Aesthet Surg.2013;6:12–16. doi: 10.4103/0974-2077.110090.[PMC free article][PubMed][Cross Ref]
7.Chan KY, Lau CL, Adeeb SM, Somasundaram S, Nasir-Zahari M. A randomized, placebo-controlled, double-blind, prospective clinical trial of silicone gel in prevention of hypertrophic scar development in median sternotomy wound.Plast Reconstr Surg.2005;116:1013–1020. doi: 10.1097/01.prs.0000178397.05852.ce.[PubMed][Cross Ref]
8.O’Brien L, Pandit A. Silicon gel sheeting for preventing and treating hypertrophic and keloid scars. Cochrane Database Syst Rev. 2006;1:CD003826.[PubMed]
9.FDA. Premarket Notification Database.http://www.accessdata.fda.gov/cdrh_docs/pdf8/K083718.pdf. Accessed 8 May 2013.
10.Sawada Y, Sone K. Treatment of scars and keloids with a cream containing silicone oil.Br J Plast Surg.1990;43:683–688. doi: 10.1016/0007-1226(90)90189-7.[PubMed][Cross Ref]
11.Sawada Y, Sone K. Hydration and occlusion treatment for hypertrophic scars and keloids.Br J Plast Surg.1992;45:599–603. doi: 10.1016/0007-1226(92)90027-U.[PubMed][Cross Ref]
12.Borgognoni L. Biological effects of silicone gel sheeting.Wound Repair Regen.2002;10:118–121. doi: 10.1046/j.1524-475X.2002.00205.x.[PubMed][Cross Ref]
13.Reish RG, Eriksson E. Scars: a review of emerging and currently available therapies.Plast Reconstr Surg.2008;122:1068–1078. doi: 10.1097/PRS.0b013e318185d38f.[PubMed][Cross Ref]
14.Har-Shai Y, Lindenbaum E, Tendler M, Gamliel-Lazarovich A, Feitelberg L, Hirshowitz B. Negatively charged static electricity stimulation as a possible mechanism for enhancing the involution of hypertrophic and keloid scars.Isr Med Assoc J.1999;1:203–205.[PubMed]
15.Lyle WG. Silicone gel sheeting.Plast Reconstr Surg.2001;107:272–275. doi: 10.1097/00006534-200101000-00048.[PubMed][Cross Ref]
16.Niessen FB, Spauwen PH, Schalkwijk J, Kon M. On the nature of hypertrophic scars and keloids: a review.Plast Reconstr Surg.1999;104:1435–1458. doi: 10.1097/00006534-199910000-00031.[PubMed][Cross Ref]
17.Zouboulis CC, Blume U, Buttner P, Orfanos CE. Outcomes of cryosurgery in keloids and hypertrophic scars. A prospective consecutive trial of case series.Arch Dermatol.1993;129:1146–1151. doi: 10.1001/archderm.1993.01680300074011.[PubMed][Cross Ref]
18.Hirshowitz B, Lerner D, Moscona AR. Treatment of keloid scars by combined cryosurgery and intralesional corticosteroids.Aesthetic Plast Surg.1982;6:153–158. doi: 10.1007/BF01570635.[PubMed][Cross Ref]
19.Li-Tsang CW, Lau JC, Choi J, Chan CC, Jianan L. A prospective randomized clinical trial to investigate the effect of silicone gel sheeting (Cica-Care) on post-traumatic hypertrophic scar among the Chinese population.Burns.2006;32:678–683. doi: 10.1016/j.burns.2006.01.016.[PubMed][Cross Ref]
20.Carney SA, Cason CG, Gowar JP, et al. Cica-Care gel sheeting in the management of hypertrophic scarring.Burns.1994;20:163–167. doi: 10.1016/S0305-4179(06)80016-1.[PubMed][Cross Ref]
21.Nikkonen MM, Pitkanen JM, Al-Qattan MM. Problems associated with the use of silicone gel sheeting for hypertrophic scars in the hot climate of Saudi Arabia.Burns.2001;27:498–501. doi: 10.1016/S0305-4179(01)00004-3.[PubMed][Cross Ref]
22.Ahn ST, Monafo WW, Mustoe TA. Topical silicone gel for the prevention and treatment of hypertrophic scar.Arch Surg.1991;126:499–504. doi: 10.1001/archsurg.1991.01410280103016.[PubMed][Cross Ref]
23.Spencer JM. Case series: evaluation of a liquid silicone gel on scar appearance following excisional surgery—a pilot study.J Drugs Dermatol.2010;9:856–858.[PubMed]
24.Musgrave MA, Umraw N, Fish JS, Gomez M, Cartotto RC. The effect of silicone gel sheets on perfusion of hypertrophic burn scars.J Burn Care Rehabil.2002;23:208–214. doi: 10.1097/00004630-200205000-00010.[PubMed][Cross Ref]
25.Foo CW, Tristani-Firouzi P. Topical modalities for treatment and prevention of postsurgical hypertrophic scars.Facial Plast Surg Clin North Am.2011;3:551–557. doi: 10.1016/j.fsc.2011.06.008.[PubMed][Cross Ref]
